Technology


XCellAssay uses engineered cell lines and miniaturized measurement methods to report on biological activities of the sum total of all endogenous and exogenous bioactive compounds present in body liquids.  Thousands of BioAssays can be conducted each day in miniaturized wells to which fractions of a drop of serum or urine are added. 

As an example of just one unmet medical need for a comprehensive diagnostic, a Consensus Statement by the Endocrine Society calls for "manufacturers to develop better and more cost effective assays" for hormones, particularly androgens (testosterone and testosterone-like 'male sex' hormones).  XCellAssay's flagship product is an 'AR BioAssay' that exhibits exquisite sensitivity and accuracy for measuring the levels of all androgens in the serum or urine of any individual, male or female.  Current techniques to evaluate androgenic activities in body liquids measure just a single hormone (testosterone).  When certain pathologic conditions require the measurement of multiple androgens, the tests used today are 15-fold more expensive and less comprehensive than the AR BioAssay measurement.  Overall, the AR BioAssay provides a low cost, exquisitely accurate and convenient way to measure a pan-androgenic activity in ultra-low volumes of body liquids.

Individual consumers and their health care providers are concerned about potential exposure to a wide variety of physiologically disruptive chemicals present in our surroundings and foods.  XCellAssay is expanding these innovative methods to enable integrated measurements for a variety of other physiologic events.  Important to this goal, XCellAssay co-founders developed a cellular barcoding technology that allows a single finger-prick drop of blood, to be collected conveniently by the patient at home, to be added to a mixture of assays for a wide-ranging evaluation.  The enhanced frequency and clinical relevance of measurement permitted by these innovative technologies will allow concerned individuals, patients and their physicians to better track health status and to more rapidly implement lifestyle or treatment alterations in response to changing need.